The overall mission of the UCSD-UCLA DRC is to foster research in the prevention and treatment of diabetes and endocrine diseases and their complications and ultimately to improve the lives of endocrine patients.
This unique Center crosses institutional boundaries to harness the energy and excitement of research in diabetes, metabolism, endocrinology, and cardiovascular disease in four outstanding institutions and to serve the needs of diabetes/endocrinology researchers at:
This comprises the major components of research in these fields in Southern California. Some selective highlights over the past five years include: (1) Organization of the Pediatric Diabetes Research Center (PDRC) at UCSD along with the addition of the La Jolla Institute for Allergy and Immunology (LIAI) on the UCSD campus, which bring outstanding new faculty into the DRC, all focused exclusively on type 1 diabetes research; (2) Establishment and occupancy of the Institute for Regenerative Medicine on the UCSD campus which has a focus on human stem cell research and beta cell regeneration; (3) Major recruitments and addition of diabetes/metabolism-based scientists at both UCLA and UCSD; for example, this includes Richard Bergman and Marilyn Ader, and their respective groups, at Cedars-Sinai, Kumar Sharma at UCSD, and Matthias von Herrath at LIAI; (4) Outstanding success of our P&F awardees as they move forward and upward in their scientific careers; (5) All of our Research cores are continuously updated with new services and state-of-the-art technologies.
The DRC fosters interaction and collaboration between talented researchers at these institutions and has an important role in bringing outstanding scientists into diabetes and endocrine research. Our 109 DRC Research Base faculty have produced numerous outstanding discoveries over the past five years, as demonstrated by 108 papers published in the Cell/Science/Nature journals, 12 in the Journal of Clinical Investigation, 18 in Circulation or Circulation Research, and 59 in the Proceedings of the National Academy of Sciences. In addition, our Research Base faculty currently hold over $155 million dollars in funding for diabetes and metabolism-related research over the past project period, including 121 R01 grants and numerous program project grants and centers (17 P01s, 6 P50s, 14 U01s, and 6 U54s) among our collaborating DRC faculty.
The center is organized into five Biomedical Research Bases:
The DRC supports five Core facilities:
The Center is an important resource for education, training, raising awareness of endocrine and diabetes research. It supports: